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Alzheimers Dement 2014;10(6):844852

There are two distinct ways to vary the severity of injury, which includes altering the weight and height of the object used in WDI (Kalish and Whalen, 2016)

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Higher doses can stall the same process or even tip into toxicity over longer exposures, where free copper drifting loose from the complex starts driving oxidative damage

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To be explicit: most of the supporting data comes from animal studies and from research on thymosin beta-4 rather than head-to-head human trials of TB-500