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The autistic brain is functionally slow-wave dominant, with an inability to regulate the associated processes that are generated in the sub-cortex to reach the cortical fields [76]

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However, sustained high levels of CORT override these protective responses one by one, favoring pathways leading to injury, such as apoptosis signaling triggered by NRPL3, inadequate synthesis of ROS decomposition, nuclear accumulation of FOXO3a, and sustained activation of the Notch pathway and ERS-IRE1/XBP1 signaling pathway, all contributing to cell death

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Causes and Risk Factors Several factors can contribute to ligament laxity and rib instability: Trauma Direct trauma is one of the most common triggers

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