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Acetylcarnitine exerts antiangiogenic and anti-inflammatory effects by targeting key signaling pathways, including the VEGF/VEGFR2, NF-B, and CXCL12/CXCR4 pathways [126, 127]
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In a sensitivity analysis restricted to placebo-controlled ALC monotherapy trials (4 studies), the pooled estimate also favored ALC (SMD 2.41, 95% CI 4.43 to 0.39
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