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NCs are key cells for IVD regeneration, and can produce proteoglycans that promote IVD repair

Melanin synthesis involves tyrosinase, the rate-limiting enzyme that catalyzes the conversion of L-tyrosine to DOPA, then to dopaquinone, which polymerises to produce melanin [50]

It also assists in protein synthesis, DNA repair, enzyme function, transport, and cell maturation

Exogenous testosterone is available in multiple pharmaceutical formulations

The ACSL4/GPX4 ratio has been shown to predict ferroptosis in MS lesions, and 4-HNE adducts indicate lipid peroxidation in the AD hippocampus (Butterfield et al., 2010

According to the redox theory of aging, the ratios of GSH/GSSG and NADP+/NADPH levels are important factors that may affect longevity by modulating the cellular redox status [140]