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When any of these are altered or function less efficiently, fluid can accumulate and cause swelling

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In addition, the inverse-variance method was implemented to compute the weighted mean differences with 95% confidence intervals (CIs) for the remaining outcomes (serum levels of estrogen, progesterone, and testosterone

The male reproductive system encompasses the hypothalamicpituitarygonadal (HPG) axis, which includes parts of the brain, specifically the hypothalamus and pituitary gland, as well as the testes (11, 12)

This evidence is, however, well-known and consistent with previous observations in FMS patients undergoing different types of drug treatments [34]