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doi: 10.1093/geronj/46.5.m171

Small human trials have not revealed significant toxicity, but they also lack rigorous design and long-term surveillance

Note that 8 mg at 5 mg/mL concentration requires drawing 160 units (1.6 mL), which exceeds a standard 1 mL insulin syringe

Among GLP-1 options, compounded semaglutide from established pharmacies tends to have more consistent availability than brand-name products because compounding pharmacies can adjust production more quickly than large pharmaceutical manufacturers

Clinical research has confirmed no effect on IGF-1 levels and no negative impact on carbohydrate metabolism

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