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Interestingly, this area gets its name from its dark color, caused by high levels of neuromelanin, which is also a downstream metabolite of L-DOPA (Carballo-Carbajal et al

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Research from Russia and Eastern Europe, where DSIP has been studied more extensively than in the United States, has suggested the peptide may reduce withdrawal symptom severity and improve outcomes in opioid detoxification protocols

These are flat, square cells arranged in layers (squamous means flat, and stratified means in layers)