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Although they do not resemble other lipids, they are grouped with them because they are also hydrophobic

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In TMAO-treated macrophages, significant upregulation is observed in both M1 signature cytokines (including IL-1, IL-6, TNF-, Chemokine (C-X-C motif) ligand (CXCL) 9, and CXCL10) and key genes such as NLRP3 (77)

doi: 10.1086/511870

Choline transport for phospholipid synthesis

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