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Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

This is the number one reason injection site rotation matters

Watson and other players have fronted investigators to answer questions about the supplements program

Deficiency may also result from poor absorption, which may increase as we age

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The peptide typically remains stable for 30-45 days when refrigerated