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Although the trend is consistent, the predicted PK curves did not align well with the observed data for the 2 mg and 40 mg dose groups

Similarly to pesticides that are considered EDCs, a study showed that the plastic hazard BPA may disrupt epigenetic regulation of fggy in mouse WATS, a carbohydrate kinase gene related to obesity, by shifting its promoter toward hypomethylation state leading to transcriptional suppression (150)

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Leuk Lymphoma 64(11):1733-1741, 2023

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