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In April 2026, the FDA removed BPC-157 from its Category 2 list (substances with safety concerns that were previously restricted from compounding)

Some peptides reduce stress-axis activity, decreasing cortisol and normalizing sexual signaling

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Some in the peptide field expect Kennedy to roll back FDAs restrictions on the industry, which could include releasing a list of peptides that the agency will no longer try to keep off the market

Bone health is also a concern with GLP-1 medications, especially for women in menopause who are already at risk for bone loss

a continued downward slope suggests either the dose wasnt maximal, adherence held, or the biology stayed responsive