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doi: 10.3389/fpls.2016.00572 189 WangY.WangJ.LiZ.SongJ.LiuY.QiuY.et al

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Another consequence of UPR is the activation of SREBP-1c pathways, which results in the maintenance of liver fat accumulation and a further exacerbation of ER stress and UPR ( 3 CHM used in treatment for NAFLD NAFLD is a complex metabolic disorder that often co-occurs with other metabolic conditions such as dyslipidemia, hypertension, and diabetes mellitus (Zhao et al., 2018)

The authors speculated that excessive mitophagy inhibits the antioxidant capacity of Fas in NDP52 overexpressed cells, indicating that NDP52 aggravated neomycin-induced ototoxicity