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Int J Mol Sci 25(2):747 Calabrese EJ, Agathokleous E, Kapoor R, Dhawan G, Kozumbo WJ, Calabrese V (2021) Metformin-enhances resilience via hormesis

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Overexpression of MRP2 has been identified in platinum-resistant cancer cell lines (Taniguchi et al., 1996)

Because MMR proteins form heterodimer pairs, a 4-antibody approach targeting all 4 proteins or a 2-antibody approach targeting only heterodimer partners PMS2 (which binds to MLH1 ) and MSH6 (which binds to MSH2 ) may be used.9 , 10 Tumour MSI and IHC testing have comparable performance