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Clinical trials have demonstrated that the combination of PD-L1 inhibitors with chemotherapy or radiation can effectively eliminate tumor cells through pyroptosis induction (Reck et al., 2019)

Wang J, Zhang ZQ, Li FQ, Chen JN, Gong XT, Cao BB, et al

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Recent studies showed that the inflammatory state of PTEC after injury could aggravate ferroptosis and damage cells by downregulating glutathione metabolism genes [62]

The therapeutic use of PE in GBS is theoretically justified by the need to remove neuro-toxic inflammatory agents that cause the condition following preceding infection, and mechanisms of molecular mimicry, established in axonal forms, as described above
