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doi: 10.1074/jbc.M602048200

Human evidence: the cagrilintide component Cagrilintide has robust human weight data but no dedicated human liver-histology data

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However, recurrent bouts of such inflammation and the toxic milieu that ensues, are thought to produce cumulative damage to myelin, oligodendrocytes and neurons, leading to progressive degeneration, atrophy and increasing disability, exacerbated by failure of myelin repair