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Gonadorelin (pharmaceutical GnRH) represents another option that works at the pituitary level

In vivo studies showed that digallic acid effectively reduced urate levels and promoted uric acid excretion, and with this, safety assessments did not show any kidney damage associated with treatment with digallic acid [49]

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[61] These may include certain antiarrhythmic agents, some antibiotics such as fluoroquinolones or macrolides, antipsychotic medications, and various other drug classes

PMID: 9331879

Role of Short Term Mucosal GSH Depletion per se in Colitis Having established a mucosal GSH depletion as an early event during TNBS+ethanol-induced colitis, we next evaluated the consequences that GSH depletion per se may have on the onset of injury within the 24 hours period post TNBS+ethanol treatment