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Statistical analyses were conducted using unpaired two-tailed Students t -tests or one-way ANOVA for multiple comparisons
Upregulation of these five genes was associated with decreased OS
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doi: 10.1093/jn/nxx062
Thus, absence of GPx1 in knockout mice was found to augment neuronal damage in the middle cerebral artery occlusion ischemia-reperfusion (MCAO) model of stroke, with increased infarct volume and increased apoptosis in brains of GPx1 / mice compared with wildtype mice [106]
These findings imply that andrographolide has considerable potential for being NETs inhibitor and further a strategy for GA treatment
