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Description
Repeating and monitoring your thyroid antibody levels is not needed
Deficiencies in folate, vitamin B12, or other methyl donors can alter methylation homeostasis

For example, a study of more than 1000 people found that higher levels of the inflammatory marker C-reactive protein (CRP) were associated with a higher risk of developing cognitive impairment and dementia [35]
Around 30% of patients start with bulbar symptoms, which affect the muscles used for speaking and swallowing, leading to problems like slurred speech (dysarthria), trouble swallowing (dysphagia), and twitching of the tongue muscles (Chi et al., 2013)

Regarding the few pathways where the result seems incongruous, when analyzing their topology, it is clear that their activation by B12 is potentially beneficial to the patient

Acta 1561 , 147158 (2002)