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Accumulated ROS contributes to both sleep deterioration and aging by driving macromolecular damage, including DNA and protein degradation
Data availability The datasets generated and analysed during the current study are not publicly available due to regulation of St Lukes International Hospital, but they are available from the corresponding author on reasonable request

Subsequently, they explored the biological pathways involving differentially expressed proteins in the database, ultimately elucidating the potential impacts of lactylation modifications [61]

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Thus, the relatively higher incidence and susceptibility of old women toward OA compared to men could be explained, and this could also be attributed to iron overload (Zhang et al., 2001)
