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Zhang, M., Sun, J., Li, M

Mol Med Rep (2017) 16:57938

The toxicity of many toxic chemicals has become a significant public health hazard worldwide, inducing oxidative stress in multiple organs, particularly the liver and kidney ( The liver and kidney are essential organs that are interdependent, involved in body metabolism, detoxifying environmental pollutants and harmful chemicals, and excreting xenobiotics ( Nigella sativa ( (Nigella sativa L.) belongs to the Ranunculaceae family and typically grows in Mediterranean regions, the Middle East, Western Asia, and Eastern Europe ( Nigella sativa has widespread pharmacological and therapeutic effects, including anticancer, antioxidant, hepatoprotective ( Nigella sativa seed extract ( Nigella sativa supplementation has been shown to reduce hepatorenal injury caused by Amikacin in rabbits ( Nigella sativa seeds have protected the nephrotoxicity induced by several anti-inflammatory agents ( Nigella sativa seeds ( Nigella sativa powder has shown antioxidant capacity and modulation of Burkholderia cepacia infection in Nile tilapia ( Nigella sativa in rats ( Azathioprine is a chemotherapeutic, antimetabolic, and immunosuppressive agent that acts as an antagonist of purine metabolism ( Although various forms of Nigella sativa : extract, oil, seed, and powder have been evaluated separately by previous researchers as antidotes for hepatorenal toxicity, no one has compared their potential protective effects on hepatorenal dysfunction

10.1046/j.1365-2672.1999.00783.x [DOI] [PubMed] [Google Scholar] Lu K., Collins L
Insomnia treatment studies looking at DSIP for insomnia have produced contradictory results
published a propensity score-matched study of 1123 Mediterranean G6PD-d subjects, the largest sample size of G6PD-d subjects to date, which showed a 71% higher risk of ASCVD after controlling for available ASCVD-related covariates 19
