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Recent studies have shown that iron release via NCOA4-mediated ferritinophagy supported synthesis of ISC proteins and mitochondrial respiration, which are critical for PDAC growth [6]

Chris: I think that that sort of cycling makes a lot of sense

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Human effector CD8+ t cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy

doi: 10.1016/j.ceb.2015.01.002 [DOI] [PubMed] [Google Scholar] 43

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that regulates gene expression associated with various physiological and pathological processes, including xenobiotic metabolism, tissue development, immune response, and cellular proliferation 28