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For systemic benefit, injection wins

These are called pathogenic bacteria

Clinical studies show that individuals taking phentermine lost approximately 3% to 8% of their body weight over 12 weeks when combined with a healthy diet and regular exercise
ReMap 2022: a database of human, mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments

Qureshi, et.al

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