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Additionally, the popularity of TK modelling has thrived due to the possibility of quantitatively estimate TK and toxicodynamic (TD) variability used in risk assessment decision-making (Kreutz et al

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Furthermore, selenoproteins can be categorized into several subfamilies according to their cellular functions, including subfamilies involved in antioxidant defense, redox regulation, thyroid hormone metabolism, selenium transport and storage, selenophosphate synthesis, calcium metabolism, myogenesis, protein folding and protein amination (43, 44)