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International guidelines designate weight management (diet, exercise, behavioral changes) as first-line therapy [157]

Association Between Maternal Smoking During Pregnancy and Severe Mental Illness in Offspring

Chen L-Y, Kang Y-N, Hoang KD, Chen K-H, Chen C

SA: Conceptualization, Funding acquisition, Methodology, Supervision, Writing review & editing

Upon activation, NLRP3 engages the scaffold protein NIMA related kinase 7 (NEK7) and recruits the adaptor apoptosis-associated speck-like protein containing a CARD (PYD and CARD domain containing (PYCARD, also known as ASC)) to assemble the inflammasome complex