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Efficacy and safety of nanoparticle albumin-bound paclitaxel monotherapy after immune checkpoint inhibitor administration for advanced non-small cell lung cancer: a multicenter phase 2 clinical trial

[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Jimnez-Garduo A.M., Mendoza-Rodrguez M.G., Urrutia-Cabrera D., Domnguez-Robles M.C., Prez-Ypez E.A., Ayala-Sumuano J.T., Meza I

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77,78,83 Depletion of ALDH1L2 markedly decreases the NADPH/NADP + and GSH/GSSG ratios, reduces the circulating tumor cells in blood and alleviates the metastatic burden

Baseline biomarker assessmentincluding glutathione peroxidase activity, malondialdehyde levels, and liver enzyme profilesprovides clinical context for personalizing supplementation strategies with your healthcare provider