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"Spinal 5-HT7 receptors play an important role in the antinociceptive and antihyperalgesic effects of tramadol and its metabolite, O-Desmethyltramadol, via activation of descending serotonergic pathways"

The mean time between baseline testing and follow-up was 5 months (range = 48 months)

Lincoff AM, et al

The peptide stack calculator helps plan multi-peptide protocols
