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however, a remaining challenge is the ability to selectively induce ferroptosis in HSCs with minimal effects on healthy hepatocytes

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Protein-sulfenic and glutathione sulfenic acids result from reaction with endogenously produced ROS or RNS but usually these species are rapidly transformed in prot-SSG (GSSR) or GSSG as more stable derivatives

Mantanis, G

Grx2 is rather unique, in that depending on cell type and organism, may be present in different cellular components