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While resmetirom remains the only FDA-approved therapy to date, experimental agents such as elamipretide (SS-31) and uncoupling protein 2 (UCP2) modulators are under investigation to restore mitochondrial integrity and reduce ROS production [103106]

Two metabolites, 5-hydroxymethyl-2-furoic and furan- 2,5-dicarboxylic acids, were analyzed as markers for Aspergillus (Figure 2) and tricarballylic measurements were used as an indicator for Fusarium (Figure 3)

Therefore, a phage therapy strategy that leverages such a trade-off could result in improved clinical outcomes by decreasing bacterial burden and by selecting for surviving bacterial mutants that are less resistant to antibiotics or less virulent 8

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It is appropriate to append modifier 25 to the qualifying E/M service code whether or not the E/M and procedure were provided by the same professional