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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Awdishu L., Mehta R.L

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Many people experience withdrawal-like symptoms that are common across the GLP-1 class, and the timeline of symptom emergence follows the pharmacokinetic clearance curve

KLOW is usually started at a low dose and increased gradually during the first week or two

Such discouraging findings have prompted research efforts directed at the development of small molecules configured to penetrate the blood-brain-barrier (BBB) and stimulate brain neurotrophins