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The high expression in glia cells suggests that Grx1 is deeply involved in supportive functions [136], such as, transcription factors activation in the nucleus [137,138] and protection of Complex I from oxidative damage at the mitochondria [139]
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Testosterone further enhances these results by increasing muscle and reducing fat mass (1)
(2) SAM's Methyl Donor Function and Methylation Reactions As a universal methyl donor, SAM participates in diverse methylation reactions mediated by methyltransferases, transferring its methyl group to substrates like DNA, RNA, and proteins
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doi: 10.1371/journal.pone.0179016 26 CoreySJMindenMDBarberDLKantarjianHWangJCYSchimmerAD
