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Footnotes Online address: DISCLOSURE A Dunne, A Cerami and M Brines are employees of Araim Pharmaceuticals and have stock or stock options in the company

Heavy metal toxicity is a prevalent issue, with exposure coming from various sources, including airplanes, water, soil, and chemicals like glyphosate, making it challenging for humans to cope 1h32m27s
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doi: 10.1073/pnas.1721115115 31 CarlsonG

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Notably, NF-B-mediated transcription can compete with Nrf2 for CREB-binding proteins (CBP), thus inhibiting Nrf2 activation