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PMLhigh senescent cells, which we define as scarred cells, are flanking some parts of the tumor

The appearance of black fibers within gray fibers implies collagen type 3 fibers within reticulin fibers and the myotendinous junction is reestablished according to morphological features (Figure 9 and Figure 10), and the appearance of abundant and well-orientated collagen type 1 fibers was found (Figure 11)

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It is indeed well established that the subclinical inflammatory status induced by sleep deprivation has pathogenic implications for metabolic and CV risk factors (glucose metabolism, diabetes, hypertension, atherogenic lipid profile, endothelial dysfunction, and coronary calcification) and outcomes (stroke and coronary heart disease) 24

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