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Description
The explanation to this anomaly is that most of the ATP is utilized for fueling the oxidative phosphorylation and less ATP is secreted as steady-state in the absence of exogenous substrate

This difference helps explain why Melanotan 1 mainly affects pigmentation, while Melanotan 2 has broader effects
Biochem J 439:114
10.1016/0014-2999(95)00224-9 Eur

doi: 10.3390/ph16010026

Kuo et al., 1995)