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it is activated by rising levels of ROS and/or its substrate, i.e., GSSG

This sugar acts as a common water replacement molecules and stabilizer of biological structures by protecting cellular systems from dehydration and preventing protein aggregation and eliminating ROS 1,27,37,75

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Finally, Zhang and his team explored the use of Au NPs to intervene in the interaction within the TME of EOC

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Numerous methodologies have been documented for restructuring the TME, encompassing the enhancement of hypoxia conditions [8], regulation of the tumor extracellular matrix [9], utilization of tumor-associated fibroblast-targeting nanotherapy [10], and reconfiguration of the tumor vascular system [11]