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Furthermore, AAV-ie-mediated overexpression of the guanine nucleotide exchange factor (Net1) in supporting cells has been demonstrated to induce supporting cell proliferation and hair cell regeneration, probably rescuing hair cell damage (Zhang et al., 2023

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doi: 10.11138/FNeur/2013.28.2.107 [DOI] [PMC free article] [PubMed] [Google Scholar] 149.Checkoway H, Powers K, Smith-Weller T, Franklin GM, Longstreth WT, Jr, Swanson PD

Genetic transcription of these imperative genes supports sufficient hormonal endometrium maintenance to ensure embryo implantation and the preservation of early pregnancy ( Figure 8 The follicular environment needs FSH to prepare it for luteinization even though FSH primarily drives folliculogenesis (116, 117)