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The rate constant for the fusion construct with dithiol PfGrx C88S was about three times smaller and decreased again fivefold for monothiol PfGrx C32S/C88S (Fig

This molecule exists in two states: reduced (GSH) and oxidized (GSSG)

Swallowing peptides that are protease-sensitive can render them inactive

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Moreover, Parkin plays a role in regulating microglial and astrocyte activation (151, 152), processes that are deeply intertwined with neuroinflammation and oxidative stress, both of which can influence ferroptosis susceptibility in PD