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The bead carries cobalt Co2+ ions, so it is possible to cement the bond between the bead and the target just by using mildly oxidative conditions, such as 10 mM hydrogen peroxide for 3060 minutes

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HO-1 is one of the downstream targets of nuclear factor erythroid 2-related factor 2 (Nrf2) (Fig

doi: 10.3390/pathogens3010014 170 RodriguezCMayoJCSainzRMAntolnIHerreraFMartnVet al
Melanin-like nanoparticles alleviate ischemia-reperfusion injury in the kidney by scavenging reactive oxygen species and inhibiting ferroptosis

The targeted delivery of MK-801 was further emphasized by analysis of the top 20 differentially expressed genes derived from the top five enriched functional terms showing a similar but stronger transcriptional regulation for GLP-1MK-801 in comparison to MK-801 (Fig
