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One major limitation is the short half-life of growth factors under physiological conditions

122124 The prevalence of gastrointestinal autonomic neuropathy in diabetes patients is estimated to be between 30 and 50%

We believe future studies should aim to identify one or more reliable markers that can be applied consistently in trials of antioxidant therapy to enhance comparability across investigations

However, some studies have found that the presence of hypertension and delayed treatment are negative factors related to the effectiveness of NGF treatment [153]