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Furthermore, the study implicated Mitogen-activated protein kinases (MAPKs), specifically ERK, JNK, and p38, in ROS accumulation, which further contributed to cytotoxicity

and down-regulation of lactate dehydrogenase (LDH), Fe 2+ , malondialdehyde (MDA), and ROS 512

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Sinha RA, Khare P, Rai A, Maurya SK, Pathak A, Mohan V et al (2009) Anti-apoptotic role of omega-3-fatty acids in developing brain: perinatal hypothyroid rat cerebellum as apoptotic model

evaluation of quality of life using the Pediatric Quality of Life Inventory (PedsQL) and for children five years and older, change from baseline measures of pulmonary function and muscle strength via handheld myometry at 6 and 12 months