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Pflgers Archiv-Eur J Physiol 472:12731298

Keap1 does not control Nrf1s activity

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An additional issue is that, although numerous studies have been carried out, the majority only address the role of SIRT1 and its pharmacological regulation

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To assess whether NAC confers protection against ferroptosis in the context of cardiac aging in vivo, 18-month-old rats were treated with NAC for 4 months (Fig