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Defined as substrates selectively utilized by host microorganisms to confer health benefits, prebiotics now encompass compounds targeting diverse microbial communities, including those residing on the skin [11,12,13]

Looking beyond GLP-1 and insulin as payloads (a molecule that increasingly appears to be a poor commercial candidate), 29 at least ten companies are working on device-based solutions to administer proteins and monoclonal antibodies orally and some technologies including the RaniPill have reached Phase I

Cell Host microbe 28 , 160168 (2020)

Nitric oxide insufficiency, platelet activation, and arterial thrombosis

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Shibeshi MA, Kifle ZD, Atnafie SA