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When addressing dimeric protein targets, the ability of dimeric therapeutic agents to antagonize paired receptors within a single molecular entity potentially offers superior therapeutic efficacy and target selectivity 15,16

Dziegielewska-Gesiak S, Fatyga E, Kasiarz G, Wilczynski T, Muc-Wierzgon M, Kokot T

However, practical limits exist from injection volume, local reactions, or systemic effects

Presentation With various organ systems potentially affected, the initial presentation can be to one or more medical specialties (Table 2)

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