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He says excessive drinking over an extended time can weaken your immune system to the point where the vaccine wont function as well as it usually would
Frontiers in Pharmacology, 12, 627533.

Vial headspace management affects oxidation rates at room temperature

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Appendices Appendix 1: Literature Search Strategies Literature Search - Vitamin B12 Economic Evidence-Based Analysis Search date: June 3, 2013 Databases searched: OVID MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, EMBASE

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