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ThomasAIaconoDBonanniLDAndreamatteoGOnofrjM

By applying the same technology used to screen and test several molecules with potential efficacy against SARS-CoV-2 [30] and combining it to the concept that drives drug repurposing, we thus successfully deorphanized C5aR1 for paclitaxel and identified a new target for this drug that can mediate some of its side effects

[DOI] [PubMed] [Google Scholar] Meldrum BS

Peptide therapy should only be used under the supervision of a licensed medical provider

In 1973, Russell Doolittle (19312019) indicated that a large disordered region of fibrinogen enabled its cleavage and activation, indicating functional importance of IDR (Doolittle, 1973)