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doi: 10.1038/ejcn.2010.91 [DOI] [PubMed] [Google Scholar] 46.Cialdella-Kam L, Nieman DC, Sha W, Meaney MP, Knab AM, Shanely RA

Khatibi, A

Mitochondria, the major sources of ROS production, are necessary for lipid peroxidation and ferroptosis [145]

and Kuiperij, H.B

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Combining GLS inhibitors with targeted therapy can suppress glutamine production and asparagine synthesis via their respective metabolic pathways, restoring tumor cell sensitivity to ASNase and significantly reducing asparagine levels, thereby increasing therapeutic efficacy (221)