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No serious adverse events were reported across this spectrum, supporting the safety of both highdose loading and lowerdose maintenance regimens

A range of biophysical tools, forming a multiparametric approach, were developed to analyze various aspects of a proteins structure, including its overall shape, folding patterns (secondary structure), temporary interactions (long-range contacts), stability, and how flexible different regions are

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Gelatin zymogram assay Matrix metalloproteases were assayed using gelatin zymography as previously described [9]

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