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However, when these conditions remain unresolved, the UPR switches to proapoptotic and inflammatory pathways with persistent accumulation of misfolded proteins promoting cell death (Chen et al., 2023)

MAPK Pathway Modulation p38 MAPK pathway suppression significantly inhibits LPS-induced phosphorylation, reducing inflammatory response and cellular stress

Conclusion The growing understanding of oxidative stress mechanisms and their impact on animal and human health has intensified interest in natural antioxidants as preventive and therapeutic strategies

McMurdie, P