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Additionally, hypoxic cancer-associated fibroblasts induced blood vessel abnormalities by altering the secretion of various pro- and anti-angiogenic factors leading to changes in endothelial cell function and promoting angiogenesis (Figure 1 illustrates angiogenic activity in the tumor microenvironment

Pernicious anaemia is an autoimmune condition that affects your stomach, which means your immune system attacks the cells in your stomach that produce the intrinsic factor, a protein needed to absorb vitamin B12

"With my friends @delbigtree + @AaronSiriSG at strategy session at my home on Cape Cod" (Tweet)

They are suggestive, not definitive

With the DoD it is suggested to be between 6% and 11%

Common Side Effects While uncommon, some people may experience mild side effects after receiving a B12 injection, including[17]: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling or numbness in the hands and feet These effects are typically short-lived and resolve on their own