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Clozapine-induced reduction of l-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice

This amino acid is produced in the body and is also found in small amounts in certain types of food, like animal products

L-carnitine may support this process by: Supporting fat utilization during exercise Potentially improving endurance performance Helping maintain energy levels during a calorie deficit Clinical research shows modest reductions in body weight and fat mass in certain populations, particularly when supplementation is combined with exercise and dietary control

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Of these, 794 were excluded after abstracts screening and identified articles in languages other than English, lack of full text or being review articles, case reports, animal or in-vitro studies

doi: 10.1016/j.etap.2010.09.003 54 van der SpekAHFliersEBoelenA