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GHK-Cu consists of glycine-histidine-lysine to form the naturally occurring copper tripeptide-1

This review systematically elucidates how the microbiota-ENS axis modulates the function of the ENS through multilevel signaling transduction involving microbial metabolites (SCFAs, BAs), intestinal hormones (GLP-1, CCK, leptin, ghrelin), and neurotransmitters (5-HT, Ach, VIP, NO, GABA), thereby regulating gastrointestinal motility

Very often these issues are stemming from misalignment of the feet, and can be easily addressed with custom orthotic inserts

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This can last for 1-2 weeks and settles once the vitamin B12 supplements have been stopped